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The original Flash version has a lean, mean item pool. Every item felt impactful because there were no "pure trash" tier pickups. The game ended at Mom’s Heart/It Lives. No Corpse, no Downpour, no alternate paths.
Most players and reviewers from sites like Steam and community forums like Reddit agree that the remake surpasses the Flash original in almost every technical and mechanical category: The Binding of Isaac on Steam
New game = Better features. Flash game = Better vibes?