You may need to grant "All files access" permission to J2ME Loader. This is safe as the emulator is widely trusted.
The game saw several releases across different mobile ecosystems: Degeneration (game) - Resident Evil Wiki download resident evil degeneration game for mobile
Unless you have an old jailbroken iPhone 4 or 5 lying around, playing the original Degeneration game on a modern iPhone is frustrating. You are better off playing the alternatives listed below. You may need to grant "All files access"